What are the Differences between Serum and Plasma?
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Serum and plasma are types of blood specimens that are utilized in testing for the concentrations of substances in the blood. They are supernatant fluids obtained after centrifugation of clotted blood and noncoagulated blood, respectively.
Here are some differences between serum and plasma:
| Category |
Serum |
Plasma |
| color |
light yellow |
lighter |
| transparency |
clearer than plasma |
less clear than serum |
| Serum protein present |
albumin, globulin |
albumin, globulin, fibrinogen |
| anticoagulant |
absent |
present |
Why is serum generally the most preferred blood specimen for clinical chemistry tests?
Serum is the preferred specimen because they have fewer proteins, which are considered as interfering substances for some tests.
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